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Functional PEGs

CHO-PEG-MAL, Aldehyde-PEG-Maleimide, MW 1,000

Catalog: TASK-03-2000109   CAS NO.: N/A
  • 500mg
  • 1g

$68.25$68.25

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Description

CHO-PEG-MAL (Aldehyde-PEG-Maleimide, ALD-PEG-MAL) is a thiol (-SH) and N-terminal amine group PEGylation reagent. Maleimide group reacts with sulfhydryl (thiol) group at pH 6.5-7.5 rapidly and specifically while aldehyde group reacts with the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEGylated maleimide and aldehydes are water soluble and all reactions can be carried out in aqueous buffer. Aldehyde reacts with n-terminus amine groups at a pH of from 5.0 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups.

Specifications

CAS No.N/A
FormulaN/A
Molecular Weight1,000
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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