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PEG Linkers with Small Molecular

TCO-PEG12-DBCO

Catalog: TASK-18-2000284   CAS NO.: 2055022-06-3
  • 5mg
  • 10mg

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Description

TCO-PEG12-DBCO refers to a compound with trans-cyclooctene, a PEG12 spacer, and dibenzylcyclooctyne functional groups linked together. TCO is a strained alkene molecule that can react with tetrazines via a rapid and bioorthogonal reaction known as tetrazine-trans-cyclooctene cycloaddition (TTCO). PEG spacers are commonly used in bioconjugation to increase solubility, flexibility, and biocompatibility of molecules. In this context, PEG12 likely serves as a flexible linker. DBCO is another strained alkyne similar to TCO, often used in bioconjugation chemistry. DBCO can react with azides via strain-promoted azide-alkyne cycloaddition (SPAAC), another bioorthogonal reaction.

Specifications

CAS No.2055022-06-3
FormulaC54H81N3O16
Molecular Weight1028.3
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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