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Biotinylation Reagents

Biotin-IETD-FMK

Catalog: TASK-36-1000594   CAS NO.: N/A
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Description

Biotin-IETD-FMK combines biotin with the caspase-8 specific tetrapeptide sequence IETD and the FMK moiety. IETD is a tetrapeptide sequence that serves as a substrate for caspase-8, a key enzyme involved in the initiation of apoptosis (programmed cell death). FMK is a chemical group that irreversibly inhibits the activity of caspases by covalently binding to their active site cysteine residues. Biotin-IETD-FMK is used to study the involvement of caspase-8 in apoptotic signaling pathways, particularly in response to death receptor activation (extrinsic pathway).

Specifications

CAS No.N/A
FormulaC38H62FN7O12S
Molecular Weight860.0
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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