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APIs & Intermediates

Bizelesin | CAS 129655-21-6

Catalog: TASK-37-1000022   CAS NO.: 129655-21-6
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Description

Bizelesin (N,N'-Bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea / (8S,8'S)-6,6'-[Carbonylbis(imino-1H-indole-5,2-diylcarbonyl)]bis[8-(chloromethyl)-3,6,7,8-tetrahydro-1-methylbenzo[1,2-b:4,3-b']dipyrrol-4-ol / NSC 615291 / U 77779) is a synthetic antitumor agent belonging to the class of DNA alkylating agents. Bizelesin has shown efficacy in preclinical studies and early clinical trials against various types of cancer, including solid tumors and hematologic malignancies. Its ability to cross-link DNA makes it effective in targeting rapidly dividing cancer cells. It also serves as a model for designing new DNA alkylating agents with improved selectivity and reduced side effects. Researchers explore structural modifications to enhance its antitumor activity and minimize toxicity. This product is available in kilograms. Please kindly contact us if you are in request.

Specifications

CAS No.129655-21-6
FormulaC43H36Cl2N8O5
Molecular Weight815.70
Purity>98%
Ship Within1 week
Storage Temp.4℃
Shipping4-25℃ for up to 3 weeks
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