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Click Chemistry

DOX-hyd-N3

Catalog: TASK-20-5001299   CAS NO.: N/A
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Description

DOX-hyd-N3 refers to a compound where doxorubicin (DOX), a well-known chemotherapeutic agent, is chemically modified with a hydrazone linkage and an azide group. Doxorubicin is an anthracycline antibiotic with a complex structure featuring a tetracyclic ring system. It is widely used in cancer therapy due to its ability to intercalate DNA and inhibit topoisomerase II, leading to cell death. A hydrazone linkage is formed between doxorubicin and the azide group through a hydrazone bond. This bond is typically formed through the reaction of a hydrazone precursor with doxorubicin. The azide group on DOX-hyd-N3 allows for the conjugation with carrier molecules or nanoparticles via click chemistry. This can enhance the targeted delivery of doxorubicin to specific cells or tissues, reducing off-target effects and improving therapeutic efficacy.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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