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Liposomes

DOTAP/DOPE (50/50, mol/mol) Liposomes, Lyophilized Powder

Catalog: TASK-25-6000039   CAS NO.: N/A
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Description

DOTAP/DOPE (50/50, mol/mol) Liposomes, Lyophilized Powder are a type of cationic liposome formulation composed of two main lipid components: DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) and DOPE (dioleoylphosphatidylethanolamine). This specific lipid combination is designed for various drug delivery applications, particularly those involving gene therapy, nucleic acid delivery, and immunotherapy. DOTAP is a cationic lipid, meaning it carries a positive charge at physiological pH. This positive charge enables it to interact efficiently with negatively charged molecules, such as DNA, RNA, and other anionic drugs. DOPE is a neutral phospholipid that provides structural stability to the liposomal bilayer and contributes to the fluidity and flexibility of the lipid membrane. The presence of DOPE helps to balance the positive charge of DOTAP and can influence the shape and size of the liposomes, ensuring their stability and improving their ability to fuse with cell membranes.

Specifications

CAS No.N/A
Lipid CompositionDOTAP/DOPE (50/50, mol/mol)
FormLyophilized Powder
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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