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PEG Linkers with Small Molecular

18-(Bromoacetamido-PEG4-ethylcarbamoyl)heptadecanoic-t-butyl ester

Catalog: TASK-18-1001081   CAS NO.: N/A
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Description

18-(Bromoacetamido-PEG4-ethylcarbamoyl)heptadecanoic-t-butyl ester is suitable for designing biomaterials for controlled drug delivery, particularly in cancer therapy. The bromoacetamido group enables specific bioconjugation reactions with thiol-containing biomolecules, such as targeting ligands or antibodies that recognize tumor-specific antigens. The PEG chain improves the solubility of the biomaterial and reduces its clearance by the immune system, leading to prolonged circulation time in the bloodstream. The t-butyl ester functional group serves as a protecting group for the carboxylic acid moiety. This group can be designed to undergo specific cleavage reactions in response to stimuli present in the tumor microenvironment, such as acidic pH or high concentrations of reducing agents. The heptadecanoic acid segment provides biocompatibility and stability to the biomaterial.

Specifications

CAS No.N/A
FormulaC34H65BrN2O8
Molecular Weight709.8
Purity95%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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