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Microspheres

2′-F-U Polystyrene Resin, 50-100 μm, Capacity 125-175 μmol/g

Catalog: TASK-28-5001439   CAS NO.: N/A
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Description

2′-F-U Polystyrene Resin refers to a specialized resin used in solid-phase synthesis, where uridine (U) is modified with a 2′-fluoro (F) group on the sugar moiety. This resin is typically utilized for the synthesis of modified RNA oligonucleotides and RNA analogs. Uridine is one of the four primary nucleosides found in RNA. It consists of the pyrimidine base uracil attached to a ribose sugar. Uridine forms complementary base pairs with adenine in RNA. The fluorine atom replaces the 2′-hydroxyl group, which increases the stability of the oligonucleotide. In natural RNA, the hydroxyl group at the 2′ position is prone to attack by nucleophiles, leading to RNA degradation through hydrolysis. The fluorine substitution makes the oligonucleotide more resistant to cleavage by nucleases, protecting it from enzymatic degradation. Polystyrene resin is an essential material for a wide range of uses in research, diagnostics, medical devices, and multiple industial applications from packaging to construction. Taskcm can provide polystyrene resins in kilograms. Please contact us if you are in need of this product.

Specifications

CAS NoN/A
Particle Size50-100 μm
Ship Within1-3 week
Storage Temp.room temperature
Shipping4-25℃ for up to 3 weeks
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