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Microspheres

2′-OMe-G(iBu) Polystyrene Resin, 50-100 μm, Capacity 125-175 μmol/g

Catalog: TASK-28-5001409   CAS NO.: N/A
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Description

2′-OMe-G(iBu) Polystyrene Resin is characterized by the presence of a 2′-O-methyl (2′-OMe) group and an isobutyl (iBu) linker, making it suitable for the incorporation of various nucleotide modifications during the synthesis process. The 2′-O-methyl modification is introduced at the ribose sugar of nucleotides and is known to enhance the stability and binding affinity of oligonucleotides. This modification provides increased resistance to enzymatic degradation, making 2′-OMe nucleotides particularly useful in therapeutic and research applications. The resin is functionalized specifically with guanine (G) nucleobases, allowing for the synthesis of oligonucleotides containing guanine residues. The choice of guanosine as the base ensures that the resulting oligonucleotide can form stable interactions with complementary sequences. The isobutyl linker connects the guanosine nucleobase to the polystyrene backbone. This linker is chosen for its stability during synthesis while allowing for efficient cleavage of the oligonucleotide product at the end of the synthesis process. Polystyrene resin is an essential material for a wide range of uses in research, diagnostics, medical devices, and multiple industial applications from packaging to construction. Taskcm can provide polystyrene resins in kilograms. Please contact us if you are in need of this product.

Specifications

CAS NoN/A
Particle Size50-100 μm
Ship Within1-3 week
Storage Temp.room temperature
Shipping4-25℃ for up to 3 weeks
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