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APIs & Intermediates

3-N-Carboxylic Acid 1-β-D-Glucuronide-[4-(methyl)phenyl]carbamate Ester Doxorubicin | CAS 211364-63-5

Catalog: TASK-37-1000914   CAS NO.: 211364-63-5
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Description

3-N-Carboxylic Acid 1-β-D-Glucuronide-[4-(methyl)phenyl]carbamate Ester Doxorubicin ((8S,10S)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-[[(β-D-glucopyranuronosyloxy)carbonyl]amino]phenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione) is valuable in improving the efficacy and safety of doxorubicin in cancer therapy, as well as in various research contexts. The β-D-glucuronide group increases the solubility of the drug in aqueous solutions, which is beneficial for intravenous administration. It also can improve the stability of the drug in the bloodstream, reducing degradation and enhancing its bioavailability. The carboxylic acid and carbamate ester groups may allow for controlled release of doxorubicin. The ester bond can be cleaved enzymatically or chemically, leading to the release of doxorubicin in a controlled manner. This controlled release can help maintain therapeutic levels over an extended period and reduce the frequency of dosing. This product is available in kilograms. Please kindly contact us if you are in request.

Specifications

CAS No.211364-63-5
FormulaC42H44N2O21
Molecular Weight912.80
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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