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APIs & Intermediates

6′-Carboxy Simvastatin-d6 | CAS 1346600-14-3

Catalog: TASK-37-1000099   CAS NO.: 1346600-14-3
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Description

6'-Carboxy Simvastatin-d6 ([2R-[2α,4α,4aβ,5β(2R*,4R*),6β]]-4-[2,2-(Dimethyl-d6)-1-oxobutoxy]-2,3,4,4a,5,6-hexahydro-6-methyl-5-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-2-naphthalenecarboxylic Acid) is a deuterated derivative of simvastatin with potential advantages in pharmacokinetic stability and metabolic studies. Simvastatin is a lipid-lowering agent that inhibits HMG-CoA reductase, the enzyme responsible for cholesterol synthesis in the liver. It has a lactone ring that is hydrolyzed to the active beta-hydroxyacid form in the body. The deuterium labeling allows researchers to track the metabolic fate of the compound in the body more precisely. It helps in understanding the drug’s absorption, distribution, metabolism, and excretion (ADME) profile. This product is available in kilograms. Please kindly contact us if you are in request.

Specifications

CAS No.1346600-14-3
FormulaC25H30D6O7
Molecular Weight454.59
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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