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Ansamitocin P 3

Catalog: TASK-21-2000051   CAS NO.: 66584-72-3
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Description

Ansamitocin P 3 is a member of the ansamycin family of compounds, which are naturally occurring secondary metabolites produced by various microorganisms, including Actinosynnema pretiosum and Nocardia. Ansamitocin P-3 exhibits potent cytotoxic activity against cancer cells by disrupting microtubule assembly, leading to cell cycle arrest and apoptosis. This mechanism of action is similar to other maytansinoids, such as DM1 and DM4. Additionally, it can serve as a precursor for the semi-synthesis of maytansinoids, including DM1 and DM4. Through chemical modifications, such as reduction and acetylation, ansamitocin P-3 can be converted into these more potent cytotoxic agents.

Specifications

CAS No.66584-72-3
FormulaC32H43ClN2O9
Molecular Weight635.2
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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