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APIs & Intermediates

AR-C 118925XX | CAS 216657-60-2

Catalog: TASK-37-1000594   CAS NO.: 216657-60-2
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Description

AR-C 118925XX (5-[[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-2H-tetrazol-5-yl-2-furancarboxamide / 5-[[5-(2,8-dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl]-N-1H-tetrazol-5-yl-2-furancarboxamide (9CI) / AR-C 118925) features a core structure typical of DHFR inhibitors, which often includes a pteridine or related heterocyclic ring system. The specific structure of AR-C 118925XX includes modifications that enhance its potency and selectivity for DHFR. AR-C 118925XX can induce cell cycle arrest and apoptosis in rapidly dividing cancer cells by interfering with DNA synthesis. This is particularly useful in treating cancers that are highly dependent on folate metabolism. This product is available in kilograms. Please kindly contact us if you are in request.

Specifications

CAS No.216657-60-2
FormulaC28H23N7O3S
Molecular Weight537.59
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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