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PEG Linkers with Small Molecular

Azido-PEG8-Amido-Val-Cit-PAB | CAS 2356229-77-9

Catalog: TASK-18-1003037   CAS NO.: 2356229-77-9
  • 250mg
  • 500mg
  • 1g

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Description

Azido-PEG8-Amido-Val-Cit-PAB is a compound designed for use in drug delivery, specifically in the development of antibody-drug conjugates (ADCs). This compound serves as a linker that connects a cytotoxic drug payload to a targeting antibody, facilitating targeted delivery of the drug to specific cells or tissues. The azido group (N₃) is a reactive functional group that can undergo bioorthogonal click chemistry reactions. This property allows for selective conjugation to complementary reactive groups, such as alkynes or alkynes modified on antibodies or drug payloads, enabling precise and controlled attachment. The amido group (-NH-CO-) serves as a linkage between the PEG8 and the Valine (Val) residue. It provides stability to the overall linker structure and ensures the integrity of the ADC during circulation in the bloodstream.

Specifications

CAS No.2356229-77-9
FormulaC40H69N9O15
Molecular Weight916.0
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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