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Click Chemistry

BCN-Lys(PEG)24-VC-PAB-MMAE

Catalog: TASK-20-5000016   CAS NO.: N/A
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Description

BCN-Lys(PEG)24-VC-PAB-MMAE refers to an advanced approach in targeted cancer therapy, leveraging bioconjugation strategies and potent cytotoxic agents. Its design emphasizes specificity in drug delivery to tumor cells, aiming to enhance therapeutic outcomes and minimize adverse effects associated with conventional chemotherapy. MMAE is a potent cytotoxic agent derived from the natural product auristatin E. It inhibits cell division by disrupting microtubule formation, making it effective in killing cancer cells. VC linker is often used in antibody-drug conjugates (ADCs) to connect the drug payload to the targeting molecule (e.g., antibody). It is designed to be stable in circulation and release the drug specifically in the target cells upon cleavage. PAB linker is a cleavable linker used in ADCs to attach the cytotoxic drug payload to the targeting molecule. It enables controlled release of the drug within the target cells, typically through enzymatic cleavage.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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