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Click Chemistry

Bis-Sulfone-PEG9-DBCO

Catalog: TASK-20-1000160   CAS NO.: N/A
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$68.25$68.25

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Description

Bis-Sulfone-PEG9-DBCO is a bis-alkylating labeling reagent that enables site-specific incorporation of DBCO moiety onto antibodies to form well-defined conjugates. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. The compound can be used in chemical biology studies where specific and selective labeling of biomolecules is required for understanding biological processes. PEGylation enhances the solubility and stability of molecules. Bis-Sulfone-PEG9-DBCO can be incorporated into drug delivery systems to improve the pharmacokinetic properties of therapeutic agents.

Specifications

CAS No.N/A
FormulaC64H79N3O17S2
Molecular Weight1226.5
Purity96%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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