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Cilofexor Tromethamine | CAS 2253764-93-9

Catalog: TASK-37-1000520   CAS NO.: 2253764-93-9
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Description

Cilofexor Tromethamine (2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid with 2-amino-2-(hydroxymethyl)propane-1,3-diol) is a pharmaceutical compound that combines cilofexor with tromethamine. Cilofexor is a selective, non-steroidal farnesoid X receptor (FXR) agonist, while tromethamine is a buffering agent used to stabilize the pH of pharmaceutical formulations. Cilofexor has shown promise in clinical trials for treating NASH, a chronic liver disease characterized by fatty liver, inflammation, and fibrosis. As an FXR agonist, cilofexor helps regulate bile acid homeostasis, reduce liver inflammation, and improve metabolic parameters. Beyond NASH, cilofexor can be beneficial for other chronic liver conditions, such as primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC), due to its effects on bile acid metabolism. This product is available in kilograms. Please kindly contact us if you are in request.

Specifications

CAS No.2253764-93-9
FormulaC32H33Cl3N4O8
Molecular Weight707.99
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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