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Biotinylation Reagents

DBCO-NHCO-PEG2-Biotin | CAS 2989400-08-8

Catalog: TASK-36-1001006   CAS NO.: 2989400-08-8
  • 50mg

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Description

DBCO-NHCO-PEG2-Biotin is primarily used in bioconjugation studies that employ click chemistry, specifically the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction with azide-functionalized molecules. This reaction is bioorthogonal, meaning it occurs selectively and efficiently in biological systems without interfering with native biomolecules. DBCO is a strained cycloalkyne group known for its rapid and selective reaction with azide groups via the copper-free click chemistry reaction, also known as the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction. This bioorthogonal reaction is highly efficient under physiological conditions and is widely used in bioconjugation studies. The NHCO linker typically refers to an amide bond (-NHCO-) that connects the DBCO group to the PEG2 spacer.

Specifications

CAS No.2989400-08-8
FormulaC35H43N5O6S
Molecular Weight661.8
Purity>98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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