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Biotinylation Reagents

Desthiobiotin-PEG4-propargyl | CAS 1951424-89-7

Catalog: TASK-36-1001055   CAS NO.: 1951424-89-7
  • 1g

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Description

Desthiobiotin-PEG4-propargyl is a molecule that combines desthiobiotin with a PEG4 linker and a propargyl group. Desthiobiotin is a biotin analog where the sulfur atom in the ureido ring is replaced by a methylene group, resulting in reduced affinity for avidin and streptavidin compared to biotin. This modification is advantageous in some applications where reversible binding is desired. Propargyl is a chemical group containing a triple bond (–C≡CH). It is reactive and can participate in click chemistry reactions, specifically azide-alkyne cycloaddition reactions (CuAAC), enabling conjugation to other molecules bearing azide groups. Desthiobiotin-PEG4-propargyl can participate in CuAAC reactions with azide-modified molecules, facilitating bioconjugation processes. This can be useful in labeling proteins, peptides, nucleic acids, or nanoparticles with desthiobiotin for various applications.

Specifications

CAS No.1951424-89-7
FormulaC21H37N3O6
Molecular Weight427.5
Purity>98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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