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APIs & Intermediates

ent-Aprepitant | CAS 172822-29-6

Catalog: TASK-37-1000196   CAS NO.: 172822-29-6
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Description

ent-Aprepitant (5-[[(2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one / [2S-[2α(R*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one / USP Aprepitant Related Compound B / Aprepitant EP Impurity D) is an enantiomer of aprepitant, a well-known antiemetic drug used primarily for the prevention of nausea and vomiting associated with chemotherapy and surgery. Aprepitant is a selective antagonist of the neurokinin-1 (NK1) receptor, which plays a crucial role in the emetic response.

Specifications

CAS No.172822-29-6
FormulaC23H21F7N4O3
Molecular Weight534.43
Purity>98%
Ship Within1 week
Storage Temp.2-8℃
Shipping4-25℃ for up to 3 weeks
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