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Biotinylation Reagents

(Lys(Me)₃⁹)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide | CAS 2022956-73-4

Catalog: TASK-36-1001594   CAS NO.: 2022956-73-4
  • 1mg

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Description

(Lys(Me)₃⁹)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide refers to a synthetic peptide that includes specific modifications and a biotin tag. It is used to study histone modifications and their effects on gene expression. Biotinylated peptides like this one can be used as probes to pull down specific modified histones from chromatin samples, followed by sequencing or analysis to understand their genomic localization. Histone H3 is a protein involved in chromatin structure and gene regulation through its modifications and interactions with DNA. Methylation at specific lysine residues is crucial for regulating chromatin structure and gene expression. Gly-Gly provides flexibility and spacing to ensure the biotin tag does not interfere with histone interactions or modifications. Biotin is a small molecule that binds strongly to streptavidin, enabling specific detection and isolation of the biotinylated peptide.

Specifications

CAS No.2022956-73-4
FormulaC117H212N43O32S+
Molecular Weight2765.3
Purity>98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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