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PEG Linkers with Small Molecular

Mal-amido-PEG5-alkyne

Catalog: TASK-18-2000071   CAS NO.: 2496687-04-6
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Description

Mal-amido-PEG5-alkyne refers to a molecule composed of three main components: a maleimide group (Mal), an amide linkage, a polyethylene glycol (PEG) linker, and an alkyne functional group. The maleimide group is known for its reactivity with thiol (-SH) groups. This allows selective conjugation to cysteine residues in proteins and peptides. The amide linkage and PEG spacer provide flexibility and water solubility, making it suitable for bioconjugation in biological environments. The alkyne group can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), a type of click chemistry. This allows for efficient and selective conjugation with azide-functionalized molecules or surfaces. The PEG linker contributes to water solubility and biocompatibility, making this compound suitable for drug delivery applications. The selective reactivity of the maleimide group with thiol-containing biomolecules can be exploited for targeted drug delivery.

Specifications

CAS No.2496687-04-6
FormulaC20H30N2O8
Molecular Weight426.5
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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