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Methyltetrazine-PEG4-Amido-PEG8-Mal-3,4-Dibromo

Catalog: TASK-20-4000041   CAS NO.: N/A
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Description

Methyltetrazine-PEG4-Amido-PEG8-Mal-3,4-Dibromo can be utilized to conjugate therapeutic molecules, such as drugs or imaging agents, to targeting moieties, such as antibodies or peptides, via bioorthogonal chemistry. The methyltetrazine group enables selective and rapid bioconjugation to trans-cyclooctene (TCO) or tetrazine-bearing targeting ligands, which can specifically recognize and bind to receptors or antigens overexpressed on the surface of diseased cells or tissues. In addition, the PEG4 and PEG8 chains incorporated into the compound provide biocompatibility and steric hindrance, which can reduce nonspecific interactions with blood components and prolong circulation time in the bloodstream. This enhances the accumulation of the drug delivery system at the target site through the enhanced permeability and retention (EPR) effect, leading to improved therapeutic efficacy and reduced side effects.

Specifications

CAS No.N/A
FormulaC40H60Br2N6O15
Molecular Weight1024.8
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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