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Polyester PEGs

PLGA-PEG-DBCO, PEG MW 2,000 & PLGA MW 10,000

Catalog: TASK-04-1000029   CAS NO.: N/A
  • 100mg
  • 250mg

$68.25$68.25

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Description

PLGA-PEG-DBCO (Poly(Lactide-co-glycolide)-b-Poly(ethylene glycol)-Dibenzocycolctyne) is a linear heterobifunctional PEGylation reagent with a PLGA and an DBCO for Cu-free chemistry. PLGA-PEG-DBCO can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalystPEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. LA/GA molar ratio will be 1:1 with no request. Specified molecular weight and molecular ratio may be offered by custom synthesis. Please contact us for more details.

Specifications

CAS No.N/A
FormulaN/A
PEG Molecular Weight2,000
PLGA Molecular Weight10,000
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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