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Biotinylation Reagents

PtdIns-(4,5)-P2-biotin (sodium salt)

Catalog: TASK-36-1001580   CAS NO.: N/A
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Description

PtdIns-(4,5)-P2-biotin (sodium salt) (DOPI-4,5-P2-biotin / Phosphatidylinositol-4,5-diphosphate C-8-biotin / PI(4,5)P2-biotin / PIP2[4′,5′]-biotin) is a biotinylated derivative of Phosphatidylinositol 4,5-bisphosphate (PtdIns-(4,5)-P2), a critical phosphoinositide involved in various cellular processes, including signal transduction, cytoskeletal organization, and membrane dynamics. PtdIns-(4,5)-P2 is a precursor for second messengers like inositol trisphosphate (IP3) and diacylglycerol (DAG), which are crucial for the regulation of various cellular processes. Biotinylated PtdIns-(4,5)-P2 is used to study these pathways in detail. Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) synthesize PtdIns-(4,5)-P2, and biotinylated PtdIns-(4,5)-P2 can be employed to investigate their activity and regulation.

Specifications

CAS No.N/A
FormulaC35H61N3O21P3S • 3Na
Molecular Weight1053.8
Purity>98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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