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Click Chemistry

ThioLinker-DBCO

Catalog: TASK-20-1000081   CAS NO.: N/A
  • 10mg
  • 25mg
  • 100mg

$68.25$68.25

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Description

ThioLinker-DBCO is a water-soluble bis-alkylating labeling reagent that enables site-specific incorporation of DBCO moiety onto antibodies to form well-defined conjugates. This approach involves two steps: (1) disulfide reduction to release the two cysteine thiols and (2) re-forming the disulfide by bis-alkylation via a three-carbon bridge to which DBCO moiety is covalently attached. During this process, irreversible denaturation of the protein, disrupting either their tertiary structure or their biological activity does not occur.

Specifications

CAS No.N/A
FormulaC59H69N3O14S3
Molecular Weight1140.4
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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