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ADC Linkers


Catalog: TASK-21-1000047   CAS NO.: N/A
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Azido-PEG8-Amido-Val-Hom(N-Boc)-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). Azide is commonly used in bioconjugation reactions, particularly in “click chemistry,” where they can react selectively with alkyne or other suitable groups. Amide bonds are commonly used for linking different molecules together, and they are found in various bioconjugation strategies. The Val-Cit is specifically cleaved by cathepsin B. N-Boc is used in organic synthesis to protect the amino group temporarily, allowing for controlled reactions. PAB is often used as a linker in drug conjugates to attach other molecules, such as cytotoxic drugs or imaging agents, to a targeting ligand.


Molecular Weight888.0
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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