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ADC Linkers


Catalog: TASK-21-1000006   CAS NO.: 870487-09-5
  • 500mg
  • 1g


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Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. The Boc group can be deprotected under acidic conditions to generate a free amine group. Boc-Val-Cit-PAB is used as a linker moiety to covalently attach a cytotoxic drug to an antibody. The PAB group allows for the attachment of the drug through an amide bond, while the tripeptide sequence provides stability and hydrophilicity to the conjugate.


CAS No.870487-09-5
Molecular Weight479.6
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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