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ADC Linkers

DBCO-PEG4-Val-Cit-PAB-PNP

Catalog: TASK-21-1000054   CAS NO.: 2226472-28-0
  • 10mg
  • 25mg

$68.25$68.25

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Description

DBCO-PEG4-Val-Cit-PAB-PNP is a multifunctional linker molecule consisting of a DBCO moiety, a PEG4 spacer, a Val-Cit dipeptide, a PAB group, and a PNP handle. The DBCO moiety enables click chemistry reactions. The Val-Cit dipeptide functions as a protease-cleavable site, and the PAB and PNP groups serve as additional conjugation handles for bioactive molecules. DBCO-PEG4-Val-Cit-PAB-PNP is employed as a versatile linker for constructing antibody-drug conjugates (ADCs). Its unique structure enables the conjugation of cytotoxic drugs to antibodies, facilitating targeted drug delivery to specific cancer cells.

Specifications

CAS No.2226472-28-0
FormulaC55H66N8O15
Molecular Weight1079.2
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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