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Lipid PEGs


Catalog: TASK-02-1000019   CAS NO.: N/A
  • 100mg
  • 500mg
  • 1g


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1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol-NHS ( DOPE-PEG-NHS, DOPE-PEG-N-Hydroxysuccinimide) is a conjugate in which a PEG chain is covalently linked to the DOPE lipid molecule, and an NHS ester group is introduced to the PEG portion. This conjugation combines the benefits of both lipid-based delivery systems and the stabilizing effects of PEGylation. The NHS group is a reactive handle that can selectively react with primary amines, such as those present in proteins, peptides, or targeting ligands. DOPE-PEG-NHS is a promising tool for creating functionalized nanoparticles or liposomes. The NHS ester group allows for controlled and specific conjugation with molecules that contain primary amines, such as lysine residues in proteins or peptides. This functionalization can be employed to attach targeting ligands, therapeutic agents, imaging agents, or other molecules to the nanoparticle surface.


Molecular Weight2,000
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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