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PEG Linkers with Small Molecular

Biotin-PEG3-SS-azide | CAS 2866429-93-6

Catalog: TASK-18-8000117   CAS NO.: 2866429-93-6
  • 10mg

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Description

Biotin-PEG3-SS-azide is a compound that combines biotin for specific binding, a PEG linker for solubility and biocompatibility, a disulfide bond for reversible conjugation, and an azide group for selective bioconjugation via click chemistry reactions. Biotin is a vitamin (Vitamin B7) known for its high affinity binding to streptavidin or avidin proteins. It serves as a specific binding tag in bioconjugation applications, enabling the detection, purification, or immobilization of biotinylated molecules. PEG (polyethylene glycol) is a hydrophilic polymer often used in bioconjugation to improve solubility, reduce non-specific interactions, and increase the circulation time of conjugated molecules in biological systems. PEG3 indicates that there are three ethylene glycol units in the PEG chain. Disulfide bonds are covalent bonds formed between two sulfur atoms and are commonly used in bioconjugation as reversible linkers. Azides are highly reactive and can undergo click chemistry reactions, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC).

Specifications

CAS No.2866429-93-6
FormulaC27H48N8O7S3
Molecular Weight692.9
Purity95%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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